• Heart Health
• Memory Function
• Muscle Function
• Immune Function
• Healthy Metabolism
• A Normal inflammatory response
Derived exclusively from edible algae, Seanol is manufactured using processes suitable for food products. Seanol has been safely consumed by tens of thousands of people with no adverse effects. Acute and chronic toxicity studies show a No Observed Adverse Effect Level (NOAEL) of 1 to 2 grams per kilogram of body weight, which represents an enormous dose for a human being. Likewise, an absence of adverse effects has been observed in pre-clinical and clinical studies.8
Seanol meets stringent specifications for purity, upper limits on microbial contamination and levels of heavy metals (lead, mercury, cadmium, arsenic). Each lot is tested for conformance to specifications and accompanied by a Certificate of Analysis showing the test results and laboratory methods utilized.
More than thirty million dollars has been invested in the research and development of Seanol. Safety and efficacy have been confirmed in an array of scientific tests that includes in-vitro and in-vivo studies, animal studies and human clinical trials.
Multiple tests and clinical trials reveal physiological effects of Seanol that optimize cardiovascular health. As an antioxidant, Seanol helps maintain healthy blood vessels by protecting the vascular epithelium from free radical attack. Phlorotannins have been shown to boost the antioxidant capacity of serum (serum reducing capacity), as measured by their ability to convert iron in the blood from the ferric form, which is a strong oxidant, to the more benign ferrous iron. Phlorotannins also benefit healthy blood vessels by retarding oxidation of LDL cholesterol and scavenging free radicals that occur in the body such as the DPPH radical and peroxynitrite.1
An open-label human clinical trial showed that Seanol supports cardiovascular health by helping to maintain open circulation in arteries, as determined by a 43% increase in flow-mediated dilation (FMD), measured in the brachial artery. (FMD measures the dilation of a blood vessel in response to blood flow through the vessel, providing a gauge of its functional status.)2 Additionally, Seanol helps maintain healthy endothelial function by regulating the renin-angiotensin-aldosterone system.3
Seanol has beneficial effects on mental energy and acuity, as demonstrated in randomized, placebo-controlled studies (unpublished). Results include improvements in cerebral circulation, optimized ratios of alpha to beta brain waves and increases in parasympathetic activity. In another set of studies, students and professional drivers taking Seanol experienced less drowsiness when studying and driving.4 Seanol raises levels of acetylcholine, one of the bodys major neurotransmitters that control memory and cognition.
Seanol has a favorable influence on the bodys physiological mechanisms that keep joints functioning in a normal state of ease and comfort. In vitro studies reveal down-regulation of prostaglandins involved in this physiology, along with inhibition of biochemical mediators of proteoglycan degradation. These findings point to a protective effect on the structural integrity of joint cartilage.5